'In Silico Toxicology' Network Meeting 2019


Supported by the British Toxicology Society (BTS), the Royal Society of Chemistry (RSC) CICAG Group, the Cambridge Alliance on Medicines Safety (CAMS) and Lhasa Ltd..

Registration on Eventbrite (closed)

An event (with free registration) to foster the In silico Toxicology Community in the UK and beyond. Scientific contributions are as welcome as those on ongoing work, regulatory aspects, industry perspectives, databases, relevant software, journals etc. in the field. This event is meant to stimulate interactions and discussions, hence speakers are asked to present both about in silico toxicology approaches that are already useful to be applied at the current stage, as well as aspects that don't work that well right now, and where future developments are hence needed.

26 November 2019, Pfizer Lecture Theatre, Department of Chemistry, University of Cambridge (CB2 1EW)

Parking: Note there is no parking available directly at the event - the Park&Rides around the city or the Queen Anne or Grand Arcade Car Parks are probably the best options if you plan to arrive by car. Otherwise the Chemistry Department is a 13 minute walk away from the station.

11-5.30pm Presentations, 5.30pm Reception, 6.15pm buffet dinner (at Chemistry Department)
(please try to stay for the reception/dinner, in addition to the scientific part this meeting is aiming to foster the in silico toxicology community in the UK and beyond)

We are planning to organize this as an informal annual event, hence please mark 30 September 2020 (New date!) in your calendar for next year's meeting.

Poster presentations for the lunch/coffee breaks are welcome - please indicate this in the registration form if desired.

Programme
10.15-11amArrival and Coffee (west/main entrance of Chemistry Department); poster setup at start of lunch break in BMS Lecture Theatre; please take posters after tea break upstairs to Cybercafe where a second set of poster boards is available
11amStart of presentations (Pfizer Lecture Theatre/at main entrance of Department)
11-11.15amWelcome (Chris Swain, Andreas Bender)
Methods
11.15-11.40Jonathan Goodman, University of Cambridge - "Computational Chemistry and Molecular Initiating Events"
11.40-12.05Elena Fioravanzo, ToxNavigation - "New Approach Methodologies in Read-Across for Toxicity Prediction: a Workflow Based on Chemoinformatics"
12.05-12.30Tim Allen, MRC Toxicology Unit - "Using Computational Chemistry in Toxicology for Safety Decision Making"
12.30-12.55Alun Myden, Lhasa Ltd. - "Using an Adverse Outcome Pathway framework to ground approaches in predictive toxicology"
1pmLunch and Posters - BMS Lecture Theatre
Applications
1.45pm-2.10pmAnton Martinsson, AstraZeneca - "Current status and future plans for ML/AI in drug safety and metabolism at AstraZeneca"
2.10pm-2.35pmSteve Gutsell, Unilever/SEAC - "Practical Application of In Silico Approaches in Next Generation Risk Assessment for Consumer Products"
2.35pm-3pmAishling Cooke, Optibrium - "Translational Toxicology: Simultaneous Data Visualisation Across Phases"
3pm-3.25pmSamar Mahmoud, University of Cambridge/Optibrium - "Understanding significant polypharmacology of chemicals inducing hepatotoxicity and acute toxicity"
Tea and Posters - BMS Lecture Theatre
Collaborations
4pm-4.25pmFiona Sewell, NC3Rs - "Using in silico approaches to support the 3Rs in safety assessment"
4.25pm-4.50pmBarry Hardy, EdelweissConnect - "International Collaboration Advancing New Methods in Predictive Toxicology and Risk Assessment"
4.50pm-ca. 5.30pmDiscussion, led by Chris Barber, Lhasa Ltd. - "Computational Approaches and AI in Toxicology - Where are we, where do we go?"
ca. 5.30pm-Reception and Posters (Cybercafe, Chemistry Department)
6.15pm-Buffet Dinner (Cybercafe, Chemistry Department)



If you have any comments or questions please contact Andreas Bender.


Hope to see you in November in Cambridge!
Cheers, Andreas