'In Silico Toxicology' Network Meeting 2019

Supported by the British Toxicology Society (BTS), the Royal Society of Chemistry (RSC) CICAG Group, the Cambridge Alliance on Medicines Safety (CAMS) and Lhasa Ltd..

Registration on Eventbrite (open until 5 November, please register in time if you wish to attend!)

An event (with free registration) to foster the In silico Toxicology Community in the UK and beyond. Scientific contributions are as welcome as those on ongoing work, regulatory aspects, industry perspectives, databases, relevant software, journals etc. in the field. This event is meant to stimulate interactions and discussions, hence speakers are asked to present both about in silico toxicology approaches that are already useful to be applied at the current stage, as well as aspects that don't work that well right now, and where future developments are hence needed.

26 November 2019, Unilever Lecture Theatre, Department of Chemistry, University of Cambridge (CB2 1EW)

10-5pm Presentations, 5-6pm Reception, followed by dinner at 6.30pm (self-paid, in walking distance from Chemistry Department)
(please try to stay for the reception/dinner, in addition to the scientific part this meeting is aiming to foster the in silico toxicology community in the UK and beyond)

We are planning to organize this as an informal annual event, hence please mark 24 November 2020 in your calendar for next year's meeting.

Poster presentations for the lunch/coffee breaks are welcome - please indicate this in the registration form if desired.

9.30-10amArrival and Coffee
10-10.30amWelcome/Overview of 'In Silico Toxicology' activities in the Cambridge Alliance on Medicines Safety (CAMS), the Computational and In Silico Toxicology Subsection of the BTS and in the Toxicology Interest Group of the RSC
10.30-5pmScientific Presentations and Discussions
Speakers and Topics
  • Graham Smith, AstraZeneca - "Current status and future plans for ML/AI in drug safety and metabolism at AstraZeneca"
  • Steve Gutsell, Unilever/SEAC - "Practical Application of In Silico Approaches in Next Generation Risk Assessment for Consumer Products"
  • Jonathan Goodman, University of Cambridge - "Computational Chemistry and Molecular Initiating Events"
  • Tim Allen, MRC Toxicology Unit - "Using Computational Chemistry in Toxicology for Safety Decision Making"
  • Samar Mahmoud, University of Cambridge/Optibrium - "Understanding significant polypharmacology of chemicals inducing hepatotoxicity and acute toxicity"
  • Elena Fioravanzo, ToxNavigation - "New Approach Methodologies in Read-Across for Toxicity Prediction: a Workflow Based on Chemoinformatics"
  • Aishling Cooke, Optibrium - "Translational Toxicology: Simultaneous Data Visualisation Across Phases"
  • Alun Myden, Lhasa Ltd. - "Using an Adverse Outcome Pathway framework to ground approaches in predictive toxicology"
  • Barry Hardy/Thomas Exner, EdelweissConnect - "The Androgen Receptor Activity Resource"
  • Fiona Sewell, NC3Rs - "Using in silico approaches to support the 3Rs in safety assessment"
  • Discussion - 'Artificial Intelligence in Computational Toxicology - What works currently, what is needed, and what will the future bring?'
  • List will be updated as additional speakers confirm their attendance and the titles of their contributions...
5-6pmReception (at the Chemistry Department)
6.30pm-Dinner (in walking distance to Chemistry Department)

If you have any comments or questions please contact Andreas Bender.

Hope to see you in November in Cambridge!
Cheers, Andreas