Dear All,
Please find below recent news about events and vacancies in our area, as well as links to some other resources related to the cheminformatics field and beyond.
In particular I would like to alert everyone to our next ‘In Silico Toxicology’ Network Meeting on 30 September 2020 – this time we will hold the event via Zoom (free and open to all), registration just opened. Please join us! See http://drugdiscovery.net/tox2020/ for details.
Events
(see also previous newsletter for some events still current:
http://www.drugdiscovery.net/2020/05/24/cambridge-cheminformatics-newsletter-24-may-2020/)
12 June – 17 September 2020
Milner Therapeutics Symposium (online, free)
26 June 2020
Putting AI into Practice (online, free)
https://www.pistoiaalliance.org/eventdetails/putting-ai-into-practice/
2 September 2020
Cambridge Cheminformatics Meeting (online, free)
We are looking for speakers for the next events, which will be both virtual and (when possible again) physically. Please let me know if you wish to present either way!
Next dates: http://www.c-inf.net
Registration open, programme TBC
https://zoom.us/meeting/register/tJEuduypqzkqHtCaYUsDkpAef1JUuzXdaQjt
21-25 September 2020
OpenTox 2020 Virtual Conference (online)
https://opentox.net/events/virtual-conference-2020
30 September 2020
In Silico Toxicology Network Meeting (online, free)
http://drugdiscovery.net/tox2020/
12 October 2020 – 10 March 2021
Pistoia Alliance Second Drug Repurposing Datathon (online, free)
https://www.pistoiaalliance.org/eventdetails/pistoia-alliance-second-drug-repurposing-datathon/
Vacancies
UK
Scientific Data Curator PDB/EMDB
EMBL, Hinxton
https://www.embl.de/jobs/searchjobs/index.php?ref=EBI01532
Data Scientist, Structural Bioinformatics
Lonza, Cambridge
https://www.lonza.com/jobs/R21897
Director of Drug Discovery
Healx, Cambridge
https://www.linkedin.com/jobs/view/1897028700/
Europe
Post Doctoral Scientist (m/w/d) Data Science/Artificial Intelligence in Drug Discovery
Sanofi
Frankfurt, Germany
Cheminformatics Data Science Group Leader
Novartis
Basel, Switzerland
https://www.novartis.com/careers/career-search/job-details/286842BR
About Cheminformatics…
Validating the validation: reanalyzing a large-scale comparison of deep learning and machine learning models for bioactivity prediction
https://link.springer.com/article/10.1007%2Fs10822-019-00274-0
So … did we crack the nut of drug discovery with deep learning and ‘AI’, or not yet? (Or don’t we know yet… or can’t we even say yet whether we know already, or not)?
Chemists: AI Is Here; Unite To Get the Benefits
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00163
The real world is sometimes quite a sober affair, isn’t it… As Ed said, “pour yourself a beverage of your choice, and mull over this one”! (https://twitter.com/griffen_ed/status/1266017635881361409)
Which ligand-protein activities cause adverse events? Interview with the author http://www.drugdiscovery.net/2020/06/15/which-ligand-protein-activities-cause-adverse-events-interview-with-the-author/
So does my drug cause side effects if it hits an ‘off-target’? Or is safety profiling simply a ‘worrying machine’? Well… it depends, and adverse event data is tricky
… and beyond:
A new treasure from my current explorations of Internet radio stations…
“Radio Improvisando”, proper Rock for the current sunny afternoons (from Columbia, but mostly music):
https://www.improvisandoradio.co/
And this is really beautiful:
Cesaria Evora – Live d’amor (Paris 2004)
https://www.youtube.com/watch?v=GrDHCxXF318
So that’s it from my side, for now. If you wish to present at one of our next Cheminformatics Meetings, whether virtually or in person, please let me know, and likewise if you have any information for me to circulate to this audience, cheers!
All the best,
Andreas